Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.66 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.66 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.66 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.66 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.64 |
| ▸ | P2RY2 | P41231 | 12/20 | 0.63 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.63 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281322 | 0.90 | SLC28A1 (0.65) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL4970785 | 0.90 | SLC28A1 (0.65) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL1532521 | 0.87 | SLC28A1 (0.74) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL8767325 | 0.86 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL15959267 | 0.86 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL121732 | 0.86 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL12259056 | 0.86 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL4849446 | 0.86 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL5612643 | 0.85 | SLC28A1 (0.71) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL12988228 | 0.85 | SLC28A1 (0.67) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931691-B1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIV HEALTH NETWORK (CA) | 2013-08-21 | — | — | EP | claimed |
| US-8067391-B2 | ODCase inhibitors for the treatment of malaria | UNIVERSITY HEALTH NETWORK (CA) | 2011-11-29 | — | — | US | claimed |
| US-20100087388-A1 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | KOTRA LAKSHMI P | 2010-04-08 | — | — | US | claimed |
| US-20090221524-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIVERSITY HEALTH NETWORK (CA) | 2009-09-03 | — | — | US | claimed |
| EP-1931691-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | University Health Network (CA) | 2008-06-18 | — | — | EP | claimed |
| WO-2007038860-A2 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | claimed |
| WO-2007038859-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | claimed |
| EP-1931691-B1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIV HEALTH NETWORK (CA) | 2013-08-21 | — | — | EP | disclosed |
| US-8067391-B2 | ODCase inhibitors for the treatment of malaria | UNIVERSITY HEALTH NETWORK (CA) | 2011-11-29 | — | — | US | disclosed |
| US-20100087388-A1 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | KOTRA LAKSHMI P | 2010-04-08 | — | — | US | disclosed |
| US-20090221524-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIVERSITY HEALTH NETWORK (CA) | 2009-09-03 | — | — | US | disclosed |
| WO-2007038860-A2 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221524-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UMPS, UGDH, UPP1 | SLC28A1 415/4885SLC28A2 455/4885SLC29A1 271/4885 |
| US-20100087388-A1 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | ITPA, DUT, MAOA | SLC28A1 1041/4885SLC28A2 1951/4885SLC29A1 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.