Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10388871 | 0.80 | PLAU (0.40) | F10PRMT1PLAUMKNK1MKNK2 | |
| SCHEMBL1387501 | 0.79 | ADORA3 (0.45) | KDM4EALDH1A1KDM6BTET3KDM4A | |
| Hydrochloric Acid SCHEMBL9792908 | 0.78 | PLAU (0.39) | F10PRMT1PLAUMKNK1MKNK2 | |
| SCHEMBL17984756 | 0.77 | PRSS1 (0.41) | F10KDM4EALDH1A1KDM6BTET3 | |
| SCHEMBL17984684 | 0.77 | F12 (0.39) | F10KDM4EALDH1A1KDM6BTET3 | |
| SCHEMBL12851523 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2PLAU | |
| SCHEMBL8153950 | 0.75 | PLAU (0.48) | KDM4EALDH1A1CYP1A2POLBSMN1; SMN2 | |
| SCHEMBL2723616 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4C | |
| Hydrochloric Acid SCHEMBL16571206 | 0.75 | PRSS1 (0.44) | ALDH1A1MAPTSMN1; SMN2PLAUMKNK1 | |
| SCHEMBL29363452 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |