Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrahydrothiophene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrothiophene SCHEMBL22158347 | 0.69 | NOS1 (0.30) | — | |
| SCHEMBL22117137 | 0.69 | NOS1 (0.30) | — | |
| Tetrahydrothiophene SCHEMBL31463996 | 0.69 | — | — | |
| Silver SCHEMBL1326350 | 0.68 | MEN1 (0.75) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6280653 | 0.68 | — | — | |
| Silver SCHEMBL961 | 0.68 | — | — | |
| Formaldehyde SCHEMBL20482146 | 0.67 | — | — | |
| SCHEMBL22556626 | 0.65 | — | — | |
| SCHEMBL31607460 | 0.65 | — | — | |
| SCHEMBL31008676 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6965045-B2 | Organic metal precursor for use in forming metal containing patterned films | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2005-11-15 | — | — | US | disclosed |
| US-20030124457-A1 | Organic metal precursor for use in forming metal containing patterned films | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2003-07-03 | — | — | US | disclosed |
| EP-1323721-A2 | Organic metal precursor for use in forming metal-containing patterned films | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2003-07-02 | — | — | EP | disclosed |