Tetrahydrothiophene

Tetrahydrothiophene

SCHEMBL22158347

C1CCSC1.C1CCSCC1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3068697 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL3067445 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL3072155 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL3068404 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL619051 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL22117137 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL3083251 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL3064622 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL3066992 1.00 NOS1 (0.30) NOS1NOS2
SCHEMBL17672286 1.00 NOS1 (0.30) NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119066270-B Barley crop planting recommendation method 陇东学院 2025-03-25 CN disclosed
CN-110230897-B Dry-heat type single-pump geothermal system and construction method thereof 河南省昌通新能源有限公司 2025-03-18 CN disclosed
CN-119066270-A Barley crop planting recommendation method 陇东学院 2024-12-03 CN disclosed
US-11202784-B2 Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency CORCEPT THERAPEUTICS, INC. (US) 2021-12-21 US disclosed
US-20200206243-A1 USE OF GLUCOCORTICOID RECEPTOR ANTAGONISTS IN COMBINATION WITH GLUCOCORTICOIDS TO TREAT ADRENAL INSUFFICIENCY CORCEPT THERAPEUTICS, INC. 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200206243-A1 USE OF GLUCOCORTICOID RECEPTOR ANTAGONISTS IN COMBINATION WITH GLUCOCORTICOIDS TO TREAT ADRENAL INSUFFICIENCY CRH, MC2R, NR3C2 NOS1 3841/4885NOS2 3480/4885
US-11202784-B2 Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency NR3C2, MC2R, NR3C1 NOS1 3797/4885NOS2 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.