Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56243 | 0.86 | GABRA1 (0.44) | ALDH1A1TSHRGABRA1GABRB2LMNA | |
| SCHEMBL50011 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TSHRGABRA1GABRB2HDAC8 | |
| SCHEMBL29717597 | 0.86 | GABRA1 (0.44) | ALDH1A1TSHRGABRA1GABRB2LMNA | |
| SCHEMBL29364896 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TSHRGABRA1GABRB2HDAC8 | |
| SCHEMBL1507296 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TSHRGABRA1GABRB2HDAC8 | |
| SCHEMBL5072506 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRGABRA1GABRB2HDAC8 | |
| SCHEMBL640982 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRGABRA1GABRB2LMNA | |
| SCHEMBL1507290 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRGABRA1GABRB2CYP1A2 | |
| SCHEMBL2064114 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRGABRA1GABRB2 | |
| SCHEMBL9772094 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855952-B2 | Semiconductor device and semiconductor package | HITACHI, LTD. (JP) | 2005-02-15 | — | — | US | disclosed |
| US-20040102636-A1 | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas | BAYER CORPORATION | 2004-05-27 | — | — | US | disclosed |
| US-20040038021-A1 | Semiconductor device and semiconductor package | HITACHI, LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102636-A1 | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas | MAP2K2, MAPK1, MAP2K1 | ALDH1A1 1875/4885TSHR 3511/4885GABRA1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.