Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | HPGD | P15428 | 8/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28773510 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL8338328 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL6177373 | 0.77 | SMN1; SMN2 (0.69) | ALDH1A1KDM4ETSHRPOLBMAPT | |
| SCHEMBL28378126 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL7729105 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL18968587 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL15569551 | 0.76 | CASR (0.73) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL28773632 | 0.75 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL28773526 | 0.75 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10TP53 | |
| SCHEMBL4622963 | 0.74 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| US-20030096826-A1 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096826-A1 | Arylsulfonamide ethers, and methods of use thereof | CASP1, IRAK1, STS | ALDH1A1 1294/4885KDM4E 1557/4885HPGD 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.