SCHEMBL6281753

SCHEMBL6281753

Cc1cc(SC(C)C)c(NC(=O)CN2CCN(CCCSc3nc4ccccc4o3)CC2)c(SC(C)C)n1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 12/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6282255 0.99 SOAT1 (0.70) SOAT1
SCHEMBL6281841 0.95 SOAT1 (0.78) SOAT1
Hydrochloric Acid SCHEMBL6282089 0.95 SOAT1 (0.77) SOAT1
SCHEMBL6286182 0.88 SOAT1 (0.91) SOAT1
SCHEMBL4983108 0.87 SOAT1 (0.61) SOAT1
SCHEMBL4984315 0.85 SOAT1 (0.65) SOAT1
SCHEMBL4983148 0.85 SOAT1 (0.66) SOAT1
SCHEMBL4987348 0.85 SOAT1 (0.66) SOAT1
SCHEMBL4985439 0.85 SOAT1 (0.66) SOAT1
SCHEMBL4987365 0.85 SOAT1 (0.66) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6969711-B2 Cyclic diamine compounds and medicine containing the same KOWA COMPANY, LTD. (JP) 2005-11-29 US disclosed
EP-0987254-B1 NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME KOWA CO (JP) 2004-12-22 EP disclosed
US-20040038987-A1 Novel cyclic diamine compounds and medicine containing the same KOWA COMPANY, LTD. (JP) 2004-02-26 US disclosed
EP-0987254-A1 NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME Kowa Co., Ltd. (JP) 2000-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038987-A1 Novel cyclic diamine compounds and medicine containing the same LCAT, ACAT2, ACAT1 SOAT1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.