Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.37 |
| ▸ | RXRB | P28702 | 9/20 | 0.37 |
| ▸ | RXRG | P48443 | 8/20 | 0.37 |
| ▸ | RARA | P10276 | 7/20 | 0.37 |
| ▸ | RARB | P10826 | 7/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275761 | 0.93 | RXRA (0.40) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6297515 | 0.91 | KDM4E (0.31) | — | |
| SCHEMBL6283174 | 0.89 | RXRA (0.37) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6284750 | 0.89 | RXRA (0.37) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6298462 | 0.85 | RARA (0.33) | RXRARXRBRXRGRARARARB | |
| SCHEMBL6363933 | 0.83 | HSP90AA1 (0.31) | — | |
| SCHEMBL6363931 | 0.83 | HSP90AA1 (0.31) | — | |
| SCHEMBL6299184 | 0.82 | PPARG (0.34) | PPARG | |
| SCHEMBL6421625 | 0.82 | PPARA (0.31) | — | |
| SCHEMBL6275730 | 0.81 | RXRA (0.39) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887896-B1 | 7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity | ALLERGAN, INC. (US) | 2005-05-03 | — | — | US | disclosed |