Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196095 | 0.84 | NPC1 (0.46) | NPC1RAB9AKMT2AHSPA5ALDH1A1 | |
| SCHEMBL6666888 | 0.83 | NPC1 (0.49) | NPC1RAB9AKMT2AHSPA5ALDH1A1 | |
| SCHEMBL7797221 | 0.83 | NPC1 (0.44) | NPC1RAB9AKMT2AHSPA5ALDH1A1 | |
| SCHEMBL10952701 | 0.81 | NPC1 (0.60) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL28882574 | 0.81 | NPC1 (0.47) | NPC1RAB9AKMT2AHSPA5ALDH1A1 | |
| SCHEMBL50972 | 0.81 | NPC1 (0.43) | NPC1RAB9AKMT2AHSPA5ALDH1A1 | |
| SCHEMBL28612372 | 0.79 | NPC1 (0.46) | NPC1RAB9AKMT2AHSPA5ALDH1A1 | |
| SCHEMBL11599997 | 0.79 | NPC1 (0.46) | NPC1RAB9AKMT2AHSPA5ALDH1A1 | |
| SCHEMBL1324 | 0.78 | NPC1 (0.62) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL2004766 | 0.78 | NPC1 (0.52) | NPC1RAB9AKMT2AHSPA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841650-B2 | Crystallizable poly (2,5-di-substituted-1,4-phenylene oxide) and a method of preparing the same | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2005-01-11 | — | — | US | disclosed |
| EP-1029882-B1 | A crystallizable poly(2,5-di-substituted-1, 4-phenylene oxide) and a method of preparing the same | NAT INST OF ADVANCED IND SCIEN (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-6541596-B1 | Subjecting a 2,5-di- substituted phenol to oxidative polymerization in the presence of oxygen and a copper complex catalyst composed of tridentate ligand of which nitrogen atoms are coordiante to a copper atom | SECRETARY OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY | 2003-04-01 | — | — | US | disclosed |
| US-20020183475-A1 | Crystallizable poly (2,5-di-substituted-1,4-phenylene oxide) and a method of preparing the same | SECRETARY OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY | 2002-12-05 | — | — | US | disclosed |
| EP-1029882-A2 | A crystallizable poly(2,5-di-substituted-1, 4-phenylene oxide) and a method of preparing the same | Secretary of Agency of Industrial Science and Technology (JP) | 2000-08-23 | — | — | EP | disclosed |