Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.66 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KARS1 | Q15046 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024094 | 0.83 | SOD1 (0.77) | SOD1NR1H2NR1H3CYP3A4KARS1 | |
| SCHEMBL15588775 | 0.83 | SOD1 (0.77) | SOD1NR1H2NR1H3CYP3A4KARS1 | |
| SCHEMBL14696167 | 0.83 | SOD1 (0.77) | SOD1NR1H2NR1H3CYP3A4KARS1 | |
| SCHEMBL2994458 | 0.82 | SOD1 (0.75) | SOD1NR1H2NR1H3CYP3A4KARS1 | |
| SCHEMBL31456047 | 0.81 | CYP3A4 (0.52) | SOD1USP2CYP3A4HSP90AA1KDM4E | |
| SCHEMBL15899658 | 0.81 | CYP3A4 (0.72) | CYP3A4MEN1TP53MAPTMAPK1 | |
| SCHEMBL6319708 | 0.81 | CYP3A4 (0.72) | CYP3A4MEN1TP53MAPTMAPK1 | |
| SCHEMBL6280790 | 0.81 | CYP3A4 (0.72) | CYP3A4MEN1TP53MAPTMAPK1 | |
| SCHEMBL12234042 | 0.80 | ENTPD5 (0.63) | SOD1NR1H2NR1H3USP2CYP3A4 | |
| SCHEMBL12234033 | 0.80 | ENTPD5 (0.63) | SOD1NR1H2NR1H3USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005239649-A | METHOD FOR PRODUCING 13-HYDROXYPODOCARPA-8,11,13-TRIENE-BASED COMPOUND | ARAKAWA CHEM IND CO LTD | 2005-09-08 | — | — | JP | disclosed |