Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 2/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819218 | 0.89 | OPRM1 (0.35) | OPRM1OPRL1EHMT2EHMT1EGFR | |
| SCHEMBL6016904 | 0.83 | BCL6 (0.48) | BCL6EHMT2KMT2AMAPTGAA | |
| SCHEMBL5032475 | 0.83 | EHMT2 (0.49) | BCL6EHMT2EHMT1ALDH1A1MAPT | |
| SCHEMBL6236057 | 0.80 | OPRM1 (0.36) | OPRM1OPRL1KMT2AMAPK1MAPT | |
| SCHEMBL6240040 | 0.78 | EGFR (0.37) | BCL6EHMT2EHMT1MAPTGAA | |
| SCHEMBL5422822 | 0.76 | BCL6 (0.47) | BCL6EHMT2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL4839057 | 0.76 | PTK2 (0.38) | BCL6EHMT2EHMT1KMT2AMAPT | |
| SCHEMBL4829119 | 0.76 | SRC (0.44) | BCL6EGFRERBB2HRH4 | |
| Hydrochloric Acid SCHEMBL6611422 | 0.74 | EHMT2 (0.45) | BCL6EHMT2EHMT1EGFR | |
| SCHEMBL4838781 | 0.74 | EHMT2 (0.41) | BCL6EHMT2EHMT1HRH4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |