Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.31 |
| ▸ | IGF1R | P08069 | 2/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6282299 | 0.89 | OPRM1 (0.38) | OPRM1OPRL1KDRFGFR1EGFR | |
| SCHEMBL4838781 | 0.85 | EHMT2 (0.41) | KDRHRH4PTK2EHMT2EHMT1 | |
| SCHEMBL6236057 | 0.72 | OPRM1 (0.36) | OPRM1OPRL1KDRFGFR1EPHX2 | |
| SCHEMBL5032475 | 0.72 | EHMT2 (0.49) | EHMT2EHMT1 | |
| SCHEMBL6016904 | 0.72 | BCL6 (0.48) | EGFREHMT2 | |
| SCHEMBL6016997 | 0.69 | IDH2 (0.43) | EGFREPHX2IGF1REHMT2CCNA2 | |
| SCHEMBL6240040 | 0.67 | EGFR (0.37) | EGFRIGF1REHMT2EHMT1INSR | |
| Hydrochloric Acid SCHEMBL6611422 | 0.67 | EHMT2 (0.45) | EGFREHMT2EHMT1CCNA2CDK2 | |
| SCHEMBL6642163 | 0.66 | EHMT2 (0.46) | EGFREHMT2EHMT1 | |
| SCHEMBL6863750 | 0.66 | EHMT2 (0.46) | PTK2EHMT2EHMT1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |