SCHEMBL6282516

SCHEMBL6282516

CCN(CC)c1ccc2cc(C#N)c(=O)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 1.00
KMT2A Q03164 11/20 1.00
MAPT P10636 9/20 1.00
KDM4E B2RXH2 8/20 1.00
CYP19A1 P11511 3/20 0.68
ALDH1A1 P00352 7/20 0.61
HPGD P15428 5/20 0.61
NPSR1 Q6W5P4 3/20 0.61
SMN1; SMN2 Q16637 5/20 0.60
ATM Q13315 5/20 0.60
USP2 O75604 4/20 0.60
GLA P06280 3/20 0.60
MAOB P27338 3/20 0.60
HSD17B10 Q99714 2/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2C19 P33261 1/20 0.60
SLC16A3 O15427 1/20 0.60
ALOX15 P16050 1/20 0.60
SLC16A1 P53985 1/20 0.60
L3MBTL1 Q9Y468 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30532621 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL4258859 0.87 MEN1 (0.78) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL12495150 0.86 MEN1 (0.76) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL11780907 0.84 MEN1 (0.72) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL11386960 0.83 KMT2A (0.71) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL28517532 0.83 MEN1 (0.70) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL9099534 0.81 CYP19A1 (0.71) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL2030045 0.80 CYP19A1 (0.75) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL5169828 0.80 CYP19A1 (0.75) MEN1KMT2AMAPTKDM4ECYP19A1
SCHEMBL13067106 0.80 CYP19A1 (0.75) MEN1KMT2AMAPTKDM4ECYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606272-A For detection of Hg 2+ Fast response type high-sensitivity fluorescent probe and preparation method thereof 陕西科技大学 2023-08-18 CN claimed
CN-119798235-A Coumarin fluorescent Huang Fensan dye and preparation method thereof 浙江迪邦化工有限公司 2025-04-11 CN disclosed
US-12083448-B2 Purification and labeling of extracellular vesicles using a mixed mode resin composition THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-09-10 US disclosed
CN-117285493-A Coumarin dye and preparation method and application thereof 浙江师范大学 2023-12-26 CN disclosed
CN-116606272-A For detection of Hg 2+ Fast response type high-sensitivity fluorescent probe and preparation method thereof 陕西科技大学 2023-08-18 CN disclosed
CN-116606272-A For detection of Hg 2+ Fast response type high-sensitivity fluorescent probe and preparation method thereof 陕西科技大学 2023-08-18 CN disclosed
EP-3731947-B1 PURIFICATION AND LABELING OF EXTRACELLULAR VESICLES USING A MIXED MODE RESIN COMPOSITION US HEALTH (US) 2023-03-01 EP disclosed
CN-108504182-B Inkjet ink composition, ink set, and recording method 精工爱普生株式会社 2021-07-02 CN disclosed
EP-3731947-A1 PURIFICATION AND LABELING OF EXTRACELLULAR VESICLES USING A MIXED MODE RESIN COMPOSITION The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2020-11-04 EP disclosed
US-20200330899-A1 PURIFICATION AND LABELING OF EXTRACELLULAR VESICLES USING A MIXED MODE RESIN COMPOSITION THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2020-10-22 US disclosed
US-10676627-B2 Ink jet ink composition and recording method SEIKO EPSON CORPORATION (JP) 2020-06-09 US disclosed
EP-3366738-B1 INK JET INK COMPOSITION AND RECORDING METHOD SEIKO EPSON CORP (JP) 2020-03-25 EP disclosed
US-20180244934-A1 INK JET INK COMPOSITION AND RECORDING METHOD SEIKO EPSON CORPORATION (JP) 2018-08-30 US disclosed
EP-3366738-A1 INK JET INK COMPOSITION AND RECORDING METHOD Seiko Epson Corporation (JP) 2018-08-29 EP disclosed
US-6962670-B1 Determination of layer thickness or non-uniformity of layer thickness based on fluorophore additives EASTMAN CHEMICAL COMPANY (US) 2005-11-08 US disclosed
EP-1180660-A2 Determination of layer thickness or non-uniformity of layer thickness based on fluorophore additives EASTMAN CHEMICAL COMPANY (US) 2002-02-20 EP disclosed
US-5091501-A Process for preparing 2H-1-benzopyran-2-ones and polyesters containing 2H-1-benzopyran-2-one residues EASTMAN KODAK COMPANY (US) 1992-02-25 US disclosed
US-3985772-A 3-Amidinocoumarin dyes BASF AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed