Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886226 | 0.87 | FDPS (0.49) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL3883365 | 0.87 | FDPS (0.49) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL10061381 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL18634692 | 0.78 | EPHX2 (0.50) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28518886 | 0.75 | MAPT (0.56) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL28930130 | 0.74 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL1879319 | 0.74 | ABCG2 (0.69) | MAPTTP53CYP1A2SMN1; SMN2FDPS | |
| SCHEMBL1879320 | 0.74 | ABCG2 (0.69) | MAPTTP53CYP1A2SMN1; SMN2FDPS | |
| SCHEMBL12035658 | 0.74 | FDPS (0.56) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL15669138 | 0.74 | FDPS (0.56) | ALDH1A1MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861050-B2 | Method of preventing darkening of skin or inhibiting melanization of melenin monomer and polymerization inhibitor of biological dihydroxyindole compound | SHISEIDO COMPANY, LTD. (JP) | 2005-03-01 | — | — | US | disclosed |
| EP-1264593-A2 | Method of preventing darkening of skin or inhibiting melanization of melanin monomer and polymerization inhibitor of biological dihydroxyindole compound | SHISEIDO COMPANY LIMITED (JP) | 2002-12-11 | — | — | EP | disclosed |