Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701341 | 0.82 | GRM2 (0.44) | GRM2GRM3CYP2D6ALOX5HPGD | |
| SCHEMBL8745906 | 0.82 | GRM2 (0.44) | GRM2GRM3CYP2D6ALOX5HPGD | |
| Hydrochloric Acid SCHEMBL8745883 | 0.80 | GRM2 (0.42) | GRM2GRM3CYP2D6ALOX5HPGD | |
| SCHEMBL3614328 | 0.78 | GRM2 (0.51) | GRM2GRM3CYP2D6ALOX5HPGD | |
| SCHEMBL8957923 | 0.78 | GRM2 (0.51) | GRM2GRM3CYP2D6ALOX5HPGD | |
| SCHEMBL3614325 | 0.78 | GRM2 (0.51) | GRM2GRM3CYP2D6ALOX5HPGD | |
| SCHEMBL28752678 | 0.77 | GRM2 (0.46) | GRM2GRM3CYP2D6ALOX5HPGD | |
| SCHEMBL3102113 | 0.76 | GRM2 (0.50) | GRM2GRM3CYP2D6ALOX5HPGD | |
| SCHEMBL3102119 | 0.76 | GRM2 (0.50) | GRM2GRM3CYP2D6ALOX5HPGD | |
| SCHEMBL28773150 | 0.75 | GRM2 (0.49) | GRM2GRM3CYP2D6ALOX5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005298337-A | METHOD FOR PRODUCING β-HYDROXYAMINO ACID DERIVATIVE AND INTERMEDIATE OF THE SAME | ONO PHARMACEUT CO LTD | 2005-10-27 | — | — | JP | disclosed |