Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701341 | 1.00 | GRM2 (0.44) | GRM2GRM3HPGDCYP2D6METAP1 | |
| Hydrochloric Acid SCHEMBL8745883 | 0.98 | GRM2 (0.42) | GRM2GRM3HPGDCYP2D6METAP1 | |
| SCHEMBL6282895 | 0.82 | GRM2 (0.53) | GRM2GRM3HPGDCYP2D6METAP1 | |
| SCHEMBL27620522 | 0.78 | GGT1 (0.46) | GRM2GRM3HPGDCYP2D6METAP1 | |
| SCHEMBL9724873 | 0.78 | GRM2 (0.40) | GRM2GRM3HPGDCYP2D6METAP1 | |
| SCHEMBL27811076 | 0.78 | ALOX5 (0.39) | GRM2GRM3HPGDMETAP1EPHX1 | |
| SCHEMBL3620882 | 0.77 | CYP1A2 (0.53) | GRM2GRM3HPGDCYP2D6METAP1 | |
| Hydrochloric Acid SCHEMBL10421626 | 0.77 | ALDH1A1 (0.39) | HPGDEPHX1SIGMAR1EPHX2 | |
| SCHEMBL27620442 | 0.76 | GGT1 (0.47) | GRM2GRM3HPGDCYP2D6METAP1 | |
| Hydrochloric Acid SCHEMBL4798850 | 0.76 | CYP1A2 (0.52) | GRM2GRM3HPGDCYP2D6METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379288-B1 | Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates | PFIZER (US) | 1993-12-22 | — | — | EP | claimed |
| EP-0519763-B1 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO PERFUMERY CO LTD (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5502221-A | HYPOTENSIVE INTERMEDIATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5442105-A | Catalytic hydrogenation, epoxidation, reacting product with trialkylsilyl azide in the presence of a Lewis acid, hydrogenolysis | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0519763-A2 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-12-23 | — | — | EP | disclosed |