Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418583 | 0.86 | PLA2G4B (0.49) | LTB4RLTB4R2L3MBTL1PLA2G4BPPARD | |
| SCHEMBL5413219 | 0.83 | PLA2G4B (0.52) | LTB4RLTB4R2L3MBTL1PLA2G4BPPARD | |
| SCHEMBL5417923 | 0.80 | PLA2G4B (0.47) | L3MBTL1PLA2G4BMAOBPPARDPPARG | |
| SCHEMBL6283120 | 0.78 | PPARG (0.46) | LTB4RL3MBTL1PPARGPPARA | |
| SCHEMBL4828857 | 0.76 | NR4A2 (0.49) | LTB4RLTB4R2PLA2G4BNPC1RAB9A | |
| SCHEMBL4828851 | 0.76 | NR4A2 (0.49) | LTB4RLTB4R2PLA2G4BNPC1RAB9A | |
| SCHEMBL11684213 | 0.74 | PLA2G4B (0.69) | LTB4RLTB4R2PLA2G4BALDH1A1LMNA | |
| SCHEMBL9517972 | 0.73 | LTB4R (0.63) | LTB4RLTB4R2PLA2G4BPPARDALDH1A1 | |
| SCHEMBL1285778 | 0.73 | PLA2G4B (0.77) | L3MBTL1PLA2G4BALDH1A1LMNA | |
| SCHEMBL11683055 | 0.72 | PLA2G4B (0.61) | LTB4RLTB4R2L3MBTL1PLA2G4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602642-A1 | IMINO ETHER DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-07 | — | — | EP | disclosed |