Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | DDO | Q99489 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481645 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL10617 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL1625559 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL4460778 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL1394237 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL248620 | 0.75 | BRD4 (1.00) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL545302 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL10285239 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL1582138 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 | |
| SCHEMBL1238471 | 0.75 | DAO (0.60) | DAOBRD4DDOKDRCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |
| EP-1091955-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-1999050263-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | disclosed |