Sugi Predict

Sugi Predict / Compounds / SCHEMBL248620

SCHEMBL248620

SCHEMBL248620

Cc1cc2ccccc2[nH]c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 1.00
▸ DAO P14920 1/20 0.60
▸ DDO Q99489 1/20 0.60
▸ KDR P35968 2/20 0.56
▸ CHEK1 O14757 1/20 0.56
▸ GRIN2D O15399 3/20 0.54
▸ GRIN3B O60391 3/20 0.54
▸ GRIN1 Q05586 3/20 0.54
▸ GRIN2A Q12879 3/20 0.54
▸ GRIN2B Q13224 3/20 0.54
▸ GRIN2C Q14957 3/20 0.54
▸ GRIN3A Q8TCU5 3/20 0.54
▸ ATAD2 Q6PL18 1/20 0.53
▸ KDM4E B2RXH2 5/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ GRM1 Q13255 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ RXFP1 Q9HBX9 1/20 0.49
▸ PDGFRB P09619 1/20 0.49
▸ FGFR1 P11362 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29979393 1.00 BRD4 (1.00) BRD4DAODDOKDRCHEK1
Hydrochloric Acid SCHEMBL30293227 0.98 BRD4 (0.96) BRD4DAODDOKDRCHEK1
Pyridine SCHEMBL11505122 0.88 BRD4 (0.77) BRD4DAODDOKDRCHEK1
SCHEMBL7879101 0.84 BRD4 (0.72) BRD4DAODDOCHEK1GRIN2D
SCHEMBL29206326 0.78 BRD4 (0.64) BRD4DAODDOKDRCHEK1
SCHEMBL16381141 0.78 DAO (0.68) BRD4DAODDOKDM4EALDH1A1
SCHEMBL15478601 0.78 DAO (0.68) BRD4DAODDOKDM4EALDH1A1
SCHEMBL1263927 0.76 KDM4E (0.66) BRD4DAODDOKDRCHEK1
SCHEMBL31154599 0.76 KDM4E (0.66) BRD4DAODDOKDRCHEK1
SCHEMBL31065667 0.76 BRD4 (0.60) BRD4KDM4EALDH1A1HPGDRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180022746-A1 INDAZOLE AND AZAINDAZOLE SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION VANDERBILT UNIVERSITY 2018-01-25 — — US claimed
CN-104693355-B Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer and synthesis method thereof 奇美实业股份有限公司 2017-08-04 — — CN claimed
EP-2661266-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES Elcelyx Therapeutics, Inc. (US) 2013-11-13 — — EP claimed
WO-2012094636-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES ELCELYX THERAPEUTICS, INC. (US) 2012-07-12 — — WO claimed
US-12582644-B2 O-GlcNAc transferase inhibitors and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-24 — — US disclosed
EP-4511117-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN Vertex Pharmaceuticals Incorporated (US) 2025-02-26 — — EP disclosed
WO-2023205465-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-10-26 — — WO disclosed
US-20230295180-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-09-21 — — US disclosed
EP-4227304-A2 THIADIAZOLE ANALOGS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH A DEFICIENCY OF SMN MOTOR NEURONS Novartis AG (CH) 2023-08-16 — — EP disclosed
WO-2023149982-A1 COMPOUNDS FOR THE TREATMENT OF SARS PURDUE RESEARCH FOUNDATION (US) 2023-08-10 — — WO disclosed
CN-115160237-A Fluorescent probe for detecting hydrogen sulfide and preparation method and application thereof 王威 2022-10-11 — — CN disclosed
CN-115023420-A Pesticidally active fused bicyclic heteroaromatic compounds 先正达农作物保护股份公司 2022-09-06 — — CN disclosed
EP-0101330-B1 2-QUINOLONE DERIVATIVES NIPPON SHINYAKU COMPANY, LIMITED (JP) 1988-08-24 — — EP disclosed
EP-0198295-A1 Vibration insulating rubber NIPPON ZEON CO., LTD. (JP) 1986-10-22 — — EP disclosed
US-4314938-A Iminoisoindolinone pigments containing phenylazoacetoacetyl-aminophenylene groups CIBA-GEIGY CORPORATION (US) 1982-02-09 — — US disclosed
US-4220586-A FASTNESS TO LIGHT, OVER-LACQUERING, MIGRATION, WEATHERING, AND HEAT CIBA-GEIGY CORPORATION (US) 1980-09-02 — — US disclosed
US-4071520-A Method for preparing carbostyril derivatives IMC CHEMICAL GROUP, INC. (US) 1978-01-31 — — US disclosed
US-4049810-A DICHLOROQUINOLINE OR QUINOLONE IMC CHEMICAL GROUP, INC. (US) 1977-09-20 — — US disclosed
US-4008086-A PYRIDONE OR PYRIDAZONE DERIVATIVES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-02-15 — — US disclosed
US-4006148-A Carbostyril derivatives used as coccidiostats IMC CHEMICAL GROUP, INC. (US) 1977-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022746-A1 INDAZOLE AND AZAINDAZOLE SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION GRIK4, GRM4, GRIA4 BRD4 127/4885DAO 1497/4885DDO 212/4885
US-20230295180-A1 PROTEIN DEGRADERS AND USES THEREOF MDM2, CUL1, PSMG3 BRD4 941/4885DAO 837/4885DDO 1755/4885
US-12582644-B2 O-GlcNAc transferase inhibitors and uses thereof OGA, OGT, OSTC BRD4 3449/4885DAO 516/4885DDO 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.