SCHEMBL6283776

SCHEMBL6283776

CNCCCCCCN1CCNC1=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.43
RAB9A P51151 1/20 0.43
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
POLB P06746 3/20 0.37
MAPT P10636 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
CREBBP Q92793 1/20 0.36
FAAH O00519 1/20 0.34
NAAA Q02083 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280206 0.98 KMT2A (0.44) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6287263 0.93 KMT2A (0.46) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6284446 0.85 KMT2A (0.51) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL2118226 0.85 ALDH1A1 (0.46) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL11173610 0.85 ALDH1A1 (0.46) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6290252 0.84 KMT2A (0.40) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6286733 0.83 KMT2A (0.42) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL7261352 0.83 ALDH1A1 (0.47) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL12385867 0.83 SMN1; SMN2 (0.44) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6287661 0.82 KMT2A (0.46) KMT2ARAB9AALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed