Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607157 | 0.89 | KMT2A (0.47) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL9607158 | 0.89 | KMT2A (0.47) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL6287263 | 0.89 | KMT2A (0.46) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL6280206 | 0.87 | KMT2A (0.44) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL6283776 | 0.85 | KMT2A (0.43) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL471729 | 0.83 | ALDH1A1 (0.50) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL6287161 | 0.83 | KMT2A (0.42) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL22030392 | 0.82 | ALDH1A1 (0.49) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL11419796 | 0.82 | KMT2A (0.49) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL6290106 | 0.81 | KMT2A (0.41) | KMT2ARAB9AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) | 2023-05-04 | — | — | US | disclosed |
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) | 2023-05-04 | — | — | US | disclosed |
| US-11135544-B2 | Acidic gas absorbent, acidic gas removal method and acidic gas removal apparatus | KABUSHIKI KAISHA TOSHIBA (JP) | 2021-10-05 | — | — | US | disclosed |
| US-11072634-B2 | Inhibitors of transglutaminases | ZEDIRA GMBH (DE) | 2021-07-27 | — | — | US | disclosed |
| US-20210147478-A1 | INHIBITORS OF BLOOD COAGULATION FACTOR XIII | ZEDIRA GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| EP-3666274-A1 | CARBOXAMIDE DERIVATIVES AND USE THEREOF | Purdue Pharma LP (US) | 2020-06-17 | — | — | EP | disclosed |
| US-20200047110-A1 | ACIDIC GAS ABSORBENT, ACIDIC GAS REMOVAL METHOD AND ACIDIC GAS REMOVAL APPARATUS | KABUSHIKI KAISHA TOSHIBA (JP) | 2020-02-13 | — | — | US | disclosed |
| EP-3221306-B1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |
| WO-2019201432-A1 | INHIBITORS OF BLOOD COAGULATION FACTOR XIII | ZEDIRA GMBH (DE) | 2019-10-24 | — | — | WO | disclosed |
| WO-2006018284-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS CATHEPSIN S INHIBITORS | NOVARTIS AG (CH) | 2006-02-23 | — | — | WO | disclosed |
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |
| WO-2004024728-A2 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-03-25 | — | — | WO | disclosed |
| EP-0734384-B1 | 3-SUBSTITUTED 1-ARYLINDOLE COMPOUNDS | LUNDBECK & CO AS H (DK) | 2000-08-09 | — | — | EP | disclosed |
| EP-0939077-A2 | 3-Substituted 1-arylindole compounds as 5-HT2 antagonists | H. LUNDBECK A/S (DK) | 1999-09-01 | — | — | EP | disclosed |
| US-5789404-A | CENTRAL NERVOUS SYSTEM DISORDERS AND ANTISEROTONIN AGENTS | H. LUNDBECK A/S (DK) | 1998-08-04 | — | — | US | disclosed |
| EP-0734384-A1 | 3-SUBSTITUTED 1-ARYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016684-A1 | 3-SUBSTITUTED 1-ARYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-06-22 | — | — | WO | disclosed |
| US-4088500-A | AMIDE-ENDCAPPED HYDROPHILIC ALKYLENE OXIDE PREPOLYMER, ACID ACTIVATED CROSSLINKING AGENT WATER, FILLER, CATALYST | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136702-A1 | Inhibitors of Human Herpesviruses | RPL5, RPL35, HAVCR2 | KMT2A 329/4885RAB9A 2843/4885ALDH1A1 1582/4885 |
| US-20210147478-A1 | INHIBITORS OF BLOOD COAGULATION FACTOR XIII | TFPI, F11, F13B | KMT2A 2770/4885RAB9A 1866/4885ALDH1A1 2881/4885 |
| US-11072634-B2 | Inhibitors of transglutaminases | TGM2, TGM3, TGM1 | KMT2A 1259/4885RAB9A 1872/4885ALDH1A1 1469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.