Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | TNFSF11 | O14788 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283907 | 1.00 | HTR6 (0.44) | HTR6PPARGTNFSF11TNFDRD2 | |
| SCHEMBL6286697 | 0.92 | HTR6 (0.46) | HTR6PPARGTNFSF11TNFDRD2 | |
| SCHEMBL6286694 | 0.92 | HTR6 (0.46) | HTR6PPARGTNFSF11TNFDRD2 | |
| SCHEMBL6278768 | 0.91 | TNFSF11 (0.46) | HTR6TNFSF11TNFDRD2HTR2A | |
| SCHEMBL6278766 | 0.91 | TNFSF11 (0.46) | HTR6TNFSF11TNFDRD2HTR2A | |
| SCHEMBL6277929 | 0.91 | PLK1 (0.42) | HTR6PPARGTNFSF11TNF | |
| SCHEMBL6277928 | 0.91 | PLK1 (0.42) | HTR6PPARGTNFSF11TNF | |
| SCHEMBL6286207 | 0.88 | HTR6 (0.43) | HTR6PPARGDRD2HTR2A | |
| SCHEMBL6286204 | 0.88 | HTR6 (0.43) | HTR6PPARGDRD2HTR2A | |
| SCHEMBL6285407 | 0.88 | HTR6 (0.44) | HTR6PPARGDRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906095-B2 | Indolylalkylidenehydrazine-carboximidamide derivatives as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2005-06-14 | — | — | US | disclosed |
| US-20040002527-A1 | Indolylalkylidenehydrazine-carboximidamide derivatives as 5-hydroxytryptamine-6 ligands | WYETH | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002527-A1 | Indolylalkylidenehydrazine-carboximidamide derivatives as 5-hydroxytryptamine-6 ligands | HTR6, HTR5A, HTR2A | HTR6 1/4885PPARG 1927/4885TNFSF11 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.