Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348623 | 0.88 | TSHR (0.52) | SMN1; SMN2HTTADRA2AADRA2BADRA2C | |
| SCHEMBL70544 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL4029852 | 0.81 | LMNA (0.62) | SMN1; SMN2MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL23483447 | 0.81 | ESR1 (0.57) | SMN1; SMN2MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL9003836 | 0.81 | TAAR1 (0.47) | TAAR1IDO1BCHEACHEALDH1A1 | |
| SCHEMBL1468357 | 0.80 | IDO1 (0.58) | LMNATAAR1TSHRIDO1LOXL2 | |
| SCHEMBL16561361 | 0.80 | IDO1 (0.58) | LMNATAAR1TSHRIDO1LOXL2 | |
| SCHEMBL7935401 | 0.79 | SRD5A2 (0.52) | TAAR1IDO1LOXL2ALDH1A1CYP3A4 | |
| SCHEMBL3452699 | 0.79 | CALM1 (0.57) | SMN1; SMN2NPC1RAB9AADRA2AADRA2B | |
| SCHEMBL6547963 | 0.79 | TSHR (0.71) | SMN1; SMN2MAPTHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112851608-B | Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound | 浙江工业大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-112851608-A | Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound | 浙江工业大学 | 2021-05-28 | — | — | CN | disclosed |
| US-6951918-B2 | Peptidic procollagen C-proteinase inhibitors | SYNTEX (U.S.A.) LLC (US) | 2005-10-04 | — | — | US | disclosed |