Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC3R | P41968 | 14/20 | 0.44 |
| ▸ | MC5R | P33032 | 13/20 | 0.44 |
| ▸ | MC4R | P32245 | 11/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GOT1 | P17174 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6290842 | 0.90 | MC3R (0.44) | MC3RMC5RMC4RHRH3GOT1 | |
| Trifluoroacetic Acid SCHEMBL6287929 | 0.87 | MC4R (0.43) | MC3RMC5RMC4RHRH3GOT1 | |
| Hydrochloric Acid SCHEMBL6290971 | 0.83 | MC4R (0.43) | MC3RMC5RMC4RHRH3 | |
| Hydrochloric Acid SCHEMBL6286771 | 0.83 | MC4R (0.43) | MC3RMC5RMC4RHRH3 | |
| SCHEMBL6286711 | 0.80 | CAMK2D (0.42) | HRH3GOT1 | |
| Trifluoroacetic Acid SCHEMBL6284172 | 0.78 | GHSR (0.45) | MC3RMC5RMC4RHRH3 | |
| Hydrochloric Acid SCHEMBL6287926 | 0.75 | MAPT (0.45) | MC3RMC5RMC4RGOT1 | |
| Hydrochloric Acid SCHEMBL6288052 | 0.75 | MC4R (0.42) | MC3RMC5RMC4RGOT1 | |
| Hydrochloric Acid SCHEMBL6287979 | 0.74 | MAPT (0.48) | MC3RMC5RMC4R | |
| Hydrochloric Acid SCHEMBL6290281 | 0.74 | MC4R (0.42) | MC3RMC5RMC4RGOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | claimed |
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | claimed |
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | claimed |
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162724-A1 | Compounds exhibiting thrombopoietin-like activities | MPL, THPO, TEK | MC3R 335/4885MC5R 517/4885MC4R 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.