Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539500 | 0.86 | ESR2 (0.47) | PPARDKDM4EALDH1A1LMNATP53 | |
| SCHEMBL6230071 | 0.86 | ESR2 (0.47) | PPARDKDM4EALDH1A1LMNATP53 | |
| SCHEMBL13352330 | 0.83 | CYP11B1 (0.42) | PPARDKDM4ETDP1ALDH1A1LMNA | |
| SCHEMBL6229912 | 0.81 | PPARD (0.40) | PPARDKDM4EALDH1A1IKBKBHPGD | |
| SCHEMBL6538959 | 0.81 | PPARD (0.40) | PPARDKDM4EALDH1A1IKBKBHPGD | |
| SCHEMBL6539133 | 0.81 | PTGS2 (0.43) | PPARDHDAC6 | |
| SCHEMBL6229835 | 0.80 | KMT2A (0.39) | PPARDKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6538578 | 0.79 | PPARD (0.54) | PPARDKDM4EALDH1A1 | |
| SCHEMBL6538981 | 0.78 | MAOB (0.54) | PPARDKDM4EALDH1A1TP53HPGD | |
| SCHEMBL6539783 | 0.78 | ALDH1A1 (0.39) | PPARDKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583749-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | Astellas Pharma Inc. (JP) | 2005-10-12 | — | — | EP | claimed |
| WO-2004065374-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | ASTELLAS PHARMA INC. (JP) | 2004-08-05 | — | — | WO | claimed |