Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284486 | 0.96 | KMT2A (0.41) | MDM2CYP1A2SRRTP53TSHR | |
| SCHEMBL14775501 | 0.83 | CYP1A2 (0.46) | MDM2CYP1A2SRRTSHRALPI | |
| SCHEMBL8147116 | 0.83 | CYP1A2 (0.46) | MDM2CYP1A2SRRTSHRALPI | |
| SCHEMBL4578730 | 0.83 | ADCYAP1R1 (0.41) | PPARGPPARA | |
| SCHEMBL7520855 | 0.81 | CAPN1 (0.49) | MDM2CYP1A2PKMNPSR1KMT2A | |
| SCHEMBL8376755 | 0.81 | ALDH1A1 (0.44) | MDM2CYP1A2SRRTSHRALPI | |
| SCHEMBL15578515 | 0.81 | ACE (0.53) | MDM2CYP1A2SRRTSHRALPI | |
| SCHEMBL9051426 | 0.78 | TSHR (0.53) | MDM2CYP1A2SRRTP53TSHR | |
| SCHEMBL15578516 | 0.77 | SLC15A1 (0.50) | CYP1A2SRRTSHRSLC6A3SLC15A1 | |
| SCHEMBL21647766 | 0.77 | TSHR (0.45) | TP53TSHRCYP2D6SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846900-B2 | POLYVALENT CARBOXYLIC ACID ESTER, PROCESS FOR PRODUCING THE CARBOXYLIC ACID ESTER, PLASTIC LENS COMPOSITION USING THE CARBOXYLIC ESTER, PLASTIC LENS OBTAINED BY CURING THE COMPOSITION AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K.K. (JP) | 2005-01-25 | — | — | US | disclosed |
| WO-2002079140-A1 | NOVEL POLYVALENT CARBOXYLIC ACID ESTERS AND THEIR USE IN PLASTIC LENS COMPOSITIONS | SHOWA DENKO K. K. (JP) | 2002-10-10 | — | — | WO | disclosed |