Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343357 | 1.00 | AGTR2 (0.52) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL9175852 | 0.96 | AGTR2 (0.53) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL9175859 | 0.96 | AGTR2 (0.53) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL6683695 | 0.90 | AGTR2 (0.55) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL16520570 | 0.86 | AGTR2 (0.47) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL3431539 | 0.85 | AGTR2 (0.51) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL12480005 | 0.85 | AGTR2 (0.51) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL21359881 | 0.85 | AGTR2 (0.51) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL16256993 | 0.85 | AGTR2 (0.51) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 | |
| SCHEMBL16256994 | 0.85 | AGTR2 (0.51) | AGTR2SMN1; SMN2NPC1RAB9APSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927294-B1 | Nitrogen-containing heterocycles | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2005-08-09 | — | — | US | disclosed |