SCHEMBL6285094

SCHEMBL6285094

C=CCc1ccc(CNC(=O)C=C)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.69
LMNA P02545 2/20 0.44
ALDH1A1 P00352 6/20 0.43
MAPK1 P28482 2/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C19 P33261 1/20 0.43
CYP1A2 P05177 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
XDH P47989 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL732934 0.90 TGM2 (0.81) TGM2LMNAALDH1A1MAPK1TSHR
SCHEMBL124217 0.83 TGM2 (0.71) TGM2LMNAALDH1A1MAPK1TSHR
SCHEMBL5933215 0.83 CYP2D6 (0.50) TGM2LMNAALDH1A1MAPK1TSHR
SCHEMBL2452377 0.83 TGM2 (0.71) TGM2LMNAALDH1A1MAPK1TSHR
SCHEMBL5933206 0.83 TGM2 (0.47) TGM2LMNAALDH1A1MAPK1TSHR
SCHEMBL9179038 0.81 TGM2 (0.69) TGM2LMNAALDH1A1MAPK1TSHR
SCHEMBL5933281 0.81 TGM2 (0.46) TGM2LMNAALDH1A1MAPK1TSHR
SCHEMBL5933288 0.81 TGM2 (0.46) TGM2LMNAALDH1A1MAPK1TSHR
SCHEMBL4927519 0.81 TGM2 (0.69) TGM2LMNAALDH1A1TDP1CYP2C19
SCHEMBL5071229 0.81 TGM2 (0.69) TGM2LMNAALDH1A1CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890625-B2 Aqueous adhesive WACKER CHEMICAL CORP (US) 2014-05-21 EP disclosed
EP-0890625-B1 Aqueous adhesive AIR PROD & CHEM (US) 2005-11-23 EP disclosed
EP-1411097-A1 Water-based adhesive compositions using waterborne polyesters AIR PRODUCTS POLYMERS, L.P. (US) 2004-04-21 EP disclosed
US-20040072003-A1 Water-based adhesive compositions using waterborne polyesters AIR PRODUCTS POLYMERS, L.P. 2004-04-15 US disclosed
US-6063858-A COMPRISING ETHYLENE-VINYL ACETATE COPOLYMER STABILIZED BY POLYVILYL ALCOHOL AND A CAST FILM; PLASTICS PACKAGING MATERIALS AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-05-16 US disclosed
US-5872181-A AN ADHESIVE COMPRISES VINYL ACETATE-ETHYLENE COPOLYMER OR TERPOLYMER WITH ETHYLENICALLY UNSATURATED COPOLYMERIZABLE MONOMER, CAST FILM OF ADHESIVE HAVE PREFERENTIAL TENSILE STORAGE MODULUS AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-02-16 US disclosed
EP-0890625-A1 Aqueous adhesive AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-01-13 EP disclosed
US-5500251-A (METH)ACRYLAMIDES AND MALEIMIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1996-03-19 US disclosed
US-5500251-A (METH)ACRYLAMIDES AND MALEIMIDES AIR PRODUCTS AND CHEMICALS, INC. (US) 1996-03-19 US disclosed