Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 3/20 | 0.60 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | RARB | P10826 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228047 | 0.96 | NR5A1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9343934 | 0.96 | NR5A1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10574379 | 0.96 | NR5A1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL10337755 | 0.96 | NR5A1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6255603 | 0.96 | NR5A1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6254577 | 0.96 | NR5A1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9330768 | 0.87 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9184595 | 0.87 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL428018 | 0.87 | LTA4H (0.78) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8436081 | 0.86 | NR5A1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005330204-A | MEGAKARYOCYTE PRODUCTION-INDUCING AGENT | OTSUKA PHARMACEUT CO LTD | 2005-12-02 | — | — | JP | disclosed |
| EP-0427166-B1 | Ester compounds and liquid crystal compositions containing the same | JAPAN ENERGY CORP (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5211879-A | ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | NIPPON MINING CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0427166-A1 | Ester compounds and liquid crystal compositions containing the same | JAPAN ENERGY CORPORATION (JP) | 1991-05-15 | — | — | EP | disclosed |