SCHEMBL428018

SCHEMBL428018

CCCCOc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.78
NR5A1 Q13285 1/20 0.78
CYP2D6 P10635 5/20 0.63
CYP3A4 P08684 4/20 0.63
CYP19A1 P11511 4/20 0.58
CYP2C9 P11712 4/20 0.58
CYP2C19 P33261 4/20 0.58
CYP1A2 P05177 3/20 0.58
RARB P10826 4/20 0.57
GPR84 Q9NQS5 1/20 0.57
ABCG2 Q9UNQ0 1/20 0.54
ESR2 Q92731 1/20 0.54
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HSD17B10 Q99714 1/20 0.51
KDM4E B2RXH2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7110214 0.96 NR5A1 (0.85) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL7736934 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL7796805 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL27889979 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL10536480 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL8178261 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL5688520 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL9225728 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL12633727 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1
SCHEMBL28107978 0.94 NR5A1 (0.89) LTA4HNR5A1CYP2D6CYP3A4CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116569084-A Polymerizable liquid crystal composition, polarizing film sheet, circularly polarizing plate, and display device 住友化学株式会社 2023-08-08 CN disclosed
CN-111656230-B Polymerizable liquid crystal composition, polarizing film and method for producing same, polarizing plate, and display device 住友化学株式会社 2022-06-24 CN disclosed
US-10996532-B2 Liquid crystal diffraction grating, liquid crystal composition, method for producing liquid crystal diffraction grating, and wire grid polarizer SHARP KABUSHIKI KAISHA (JP) 2021-05-04 US disclosed
CN-111656230-A Polymerizable liquid crystal composition, polarizing film and method for producing same, polarizing plate, and display device 住友化学株式会社 2020-09-11 CN disclosed
CN-110776859-A Structural adhesive for producing paper diapers in low-temperature environment 嘉好(太仓)新材料股份有限公司 2020-02-11 CN disclosed
WO-2019151226-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED FILM AND METHOD FOR MANUFACTURING SAME, POLARIZING PLATE, AND DISPLAY DEVICE 住友化学株式会社 2019-08-08 WO disclosed
US-20190086698-A1 LIQUID CRYSTAL DIFFRACTION GRATING, LIQUID CRYSTAL COMPOSITION, METHOD FOR PRODUCING LIQUID CRYSTAL DIFFRACTION GRATING, AND WIRE GRID POLARIZER SHARP KABUSHIKI KAISHA (JP) 2019-03-21 US disclosed
US-20170349621-A1 TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME BioVersys AG (CH) 2017-12-07 US disclosed
US-20150267119-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2015-09-24 US disclosed
EP-2921545-A2 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS Merck Patent GmbH (DE) 2015-09-23 EP disclosed
US-5401436-A Liquid crystal ASAHI DENKA KOGKO KABUSHIKI KAISHA (JP) 1995-03-28 US disclosed
US-5395910-A Photostable polymers AKZO NOBEL N.V. (NL) 1995-03-07 US disclosed
EP-0442748-B1 Improvements in and relating to leukotriene antagonists LILLY CO ELI (US) 1995-01-11 EP disclosed
US-5329034-A Silanol compounds, polymerizable monomers and polymers having mesogenic groups SAGAMI CHEMICAL RESEARCH CENTER (JP) 1994-07-12 US disclosed
EP-0550105-A2 Liquid-crystalline polyurethanes, compositions of said liquid-crystalline polyurethanes, and a device for optical data storage comprising a liquid-crystalline polyurethane Akzo Nobel N.V. (NL) 1993-07-07 EP disclosed
US-5200111-A Adjusts helical pitch of cholesteric liquid crystals ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1993-04-06 US disclosed
WO-1992012956-A1 NOVEL COMPOUNDS AND BLENDS CONTAINING THEM THE BRITISH PETROLEUM COMPANY PLC (GB) 1992-08-06 WO disclosed
EP-0471277-A2 Silanol compounds, polymerizable monomers and polymers having mesogenic groups SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-02-19 EP disclosed
EP-0442748-A1 Improvements in and relating to leukotriene antagonists ELI LILLY AND COMPANY (US) 1991-08-21 EP disclosed
US-4996230-A Antiallergens, antiinflammatory agent ELI LILLY AND COMPANY (US) 1991-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349621-A1 TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PROKR1, ARG1, ARG2 LTA4H 733/4885NR5A1 2069/4885CYP2D6 285/4885
US-20150267119-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS LPXN, VCL, LCP1 LTA4H 2014/4885NR5A1 1482/4885CYP2D6 2786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.