Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763796 | 0.87 | NPC1 (0.54) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL18704840 | 0.85 | PTGS2 (0.59) | CYP3A4CHRM1ALDH1A1PTGS2NPC1 | |
| SCHEMBL18704816 | 0.84 | CYP3A4 (0.44) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL8780191 | 0.84 | PTGS2 (0.61) | CYP3A4CHRM1ALOX15ALDH1A1PTGS2 | |
| SCHEMBL16018027 | 0.84 | PTGS2 (0.61) | CYP3A4CHRM1ALOX15ALDH1A1PTGS2 | |
| SCHEMBL18704823 | 0.84 | PTGS2 (0.61) | CYP3A4CHRM1ALOX15ALDH1A1PTGS2 | |
| SCHEMBL18704830 | 0.84 | PTGS2 (0.61) | CYP3A4CHRM1ALOX15ALDH1A1PTGS2 | |
| SCHEMBL18704811 | 0.84 | PTGS2 (0.61) | CYP3A4CHRM1ALOX15ALDH1A1PTGS2 | |
| SCHEMBL28232346 | 0.82 | CYP3A4 (0.42) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL675857 | 0.80 | CYP3A4 (0.50) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6734278-B2 | MELT ESTER INTERCHANGE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-11 | — | — | US | claimed |
| US-20030139564-A1 | Production of polyester carbonates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-24 | — | — | US | claimed |
| US-6887970-B2 | Method for producing polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | disclosed |
| US-6835797-B2 | Reacting a dihydroxyaryl compound with a diaryl carbonate to obtain a melt; flash evaporation of the monohydroxyaryl compound; heating the melt under vacuum; and repeating the steps | BAYER AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | disclosed |
| US-20040143088-A1 | Method for producing polycarbonates | COVESTRO DEUTSCHLAND AG (DE) | 2004-07-22 | — | — | US | disclosed |
| US-6734278-B2 | MELT ESTER INTERCHANGE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-11 | — | — | US | disclosed |
| US-6646099-B2 | Production and use of polyester carbonates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-11 | — | — | US | disclosed |
| US-20030139564-A1 | Production of polyester carbonates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-24 | — | — | US | disclosed |
| US-20030105272-A1 | Production and use of polyester carbonates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
| US-20020177684-A1 | Process for producing polycarbonates | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-28 | — | — | US | disclosed |
| US-20020137874-A1 | Process for producing oligocarbonates | COVESTRO DEUTSCHLAND AG (DE) | 2002-09-26 | — | — | US | disclosed |