SCHEMBL6285516

SCHEMBL6285516

CCCCC/C=C\C/C=C\CCCCCCCC(=O)NC

nearest known ligand 0.90

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
ALDH1A1 P00352 6/20 0.68
HPGD P15428 3/20 0.68
CNR1 P21554 2/20 0.68
TDP1 Q9NUW8 2/20 0.68
TRPV1 Q8NER1 1/20 0.68
MAPT P10636 1/20 0.68
ALOX12 P18054 1/20 0.68
BLM P54132 1/20 0.68
KDM4E B2RXH2 3/20 0.67
F7 P08709 3/20 0.67
F3 P13726 3/20 0.67
PPARG P37231 2/20 0.67
PPARD Q03181 2/20 0.67
PPARA Q07869 2/20 0.67
DUSP3 P51452 1/20 0.67
PTPN7 P35236 1/20 0.67
FFAR1 O14842 1/20 0.67
LMNA P02545 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30581393 1.00 MEN1 (0.69) MEN1KMT2AALDH1A1HPGDCNR1
SCHEMBL23280891 1.00 MEN1 (0.69) MEN1KMT2AALDH1A1HPGDCNR1
SCHEMBL18736051 0.98 MEN1 (0.67) MEN1KMT2AALDH1A1HPGDCNR1
SCHEMBL3634728 0.95 CNR1 (0.71) MEN1KMT2AALDH1A1HPGDCNR1
SCHEMBL3634730 0.95 CNR1 (0.71) MEN1KMT2AALDH1A1HPGDCNR1
SCHEMBL16011353 0.95 TERT (0.63) MEN1KMT2ATDP1MAPTBLM
SCHEMBL18251107 0.95 TERT (0.63) MEN1KMT2ATDP1MAPTBLM
SCHEMBL379107 0.95 TERT (0.63) MEN1KMT2ATDP1MAPTBLM
SCHEMBL4147472 0.95 TERT (0.63) MEN1KMT2ATDP1MAPTBLM
SCHEMBL23027735 0.95 TERT (0.63) MEN1KMT2ATDP1MAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267680-A1 FLUORESCENT DYES Exopharm Limited (AU) 2023-11-01 EP disclosed
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid SHIONOGI & CO., LTD. (JP) 2023-05-02 US disclosed
WO-2022133552-A1 FLUORESCENT DYES Exopharm Limited (AU) 2022-06-30 WO disclosed
EP-3960726-A1 AMINE CATIONIC LIPIDS AND USES THEREOF Dicerna Pharmaceuticals, Inc. (US) 2022-03-02 EP disclosed
EP-3597644-B1 AMINE CATIONIC LIPIDS AND USES THEREOF DICERNA PHARMACEUTICALS INC (US) 2021-09-29 EP disclosed
WO-2020191329-A1 ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-09-24 WO disclosed
EP-3603648-A1 COMPLEX OF NUCLEIC ACID MEDICINE AND MULTIBRANCHED LIPID Shionogi & Co., Ltd (JP) 2020-02-05 EP disclosed
CN-110372593-A Cannabinoid receptor antagonists/iN. V. erse agonists 詹里恩探索公司 2019-10-25 CN disclosed
CN-110290809-A Pharmaceutical dosage form comprising TASK-1 and TASK-3 channel inhibitor and its purposes for treating respiratory disorder 拜耳制药股份公司 2019-09-27 CN disclosed
CN-110191884-A Substituted 6- (1H-pyrazol-1-yl) pyrimidine-4-amine derivatives and uses thereof 拜耳公司 2019-08-30 CN disclosed
CN-101223184-B Glucuronidated nebivolol MYLAN LAB INC 2012-10-10 CN disclosed
CN-102711739-A bilayer tablet BRISTOL MYERS SQUIBB CO 2012-10-03 CN disclosed
CN-102188708-A Compositions containing nebivolol MYLAN LAB INC 2011-09-21 CN disclosed
CN-101880276-A Diazepan compounds as the replacement of orexin receptor antagonists MERCK & CO INC 2010-11-10 CN disclosed
CN-101627028-A Substituted diazepan compounds as orexin receptor antagonists MERCK & CO INC 2010-01-13 CN disclosed
CN-101490024-A Substituted phenylacetic acids as DP-2 antagonists ICOS CORP (US) 2009-07-22 CN disclosed
CN-101277960-A Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators MERCK & CO INC (US) 2008-10-01 CN disclosed
US-6852315-B2 Epoxidation of carbon-carbon double bond with membrane bound peroxygenase THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2005-02-08 US disclosed
US-20030040090-A1 Epoxidation of carbon-carbon double bond with membrane bound peroxygenase AGRICULTURE, UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY 2003-02-27 US disclosed
US-6485949-B1 Epoxidation of carbon-carbon double bond with membrane bound peroxygenase THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2002-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid FABP1, POLRMT, SREBF1 MEN1 1693/4885KMT2A 1076/4885ALDH1A1 3124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.