SCHEMBL628573

SCHEMBL628573

C=C(C)C(=O)N(O)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.53
ALOX5 P09917 5/20 0.51
PTGS1 P23219 1/20 0.51
PTGS2 P35354 1/20 0.51
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
LMNA P02545 1/20 0.46
TSPO P30536 1/20 0.44
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1629312 0.85 LMNA (0.55) NPC1RAB9ACA12CA9LMNA
SCHEMBL20644841 0.84 HTT (0.47) RIPK1ALOX5PTGS1PTGS2RAB9A
SCHEMBL9906098 0.83 LMNA (0.53) NPC1RAB9ACA12CA9LMNA
SCHEMBL2836935 0.83 NPC1 (0.59) RIPK1NPC1RAB9ACA12CA9
SCHEMBL1436622 0.82 ALOX5 (0.70) RIPK1ALOX5PTGS1PTGS2NPC1
SCHEMBL4445336 0.81 ALOX5 (0.50) RIPK1ALOX5PTGS1PTGS2NPC1
SCHEMBL3281021 0.80 NPC1 (0.47) RIPK1NPC1RAB9ACA12CA9
SCHEMBL28435736 0.80 NPC1 (0.43) NPC1RAB9ACA12CA9CRHBP
SCHEMBL28078011 0.80 NPC1 (0.56) NPC1RAB9ATSPOALDH1A1TSHR
SCHEMBL3279004 0.79 ALOX5 (0.60) RIPK1ALOX5PTGS1PTGS2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008068073-A1 STORAGE-STABLE PU POWDER COATING COMPOSITIONS AND THEIR USE FOR FLEXIBLE, LOW-HAZE POLYURETHANE COATINGS EVONIK DEGUSSA GMBH (DE) 2008-06-12 WO claimed
EP-1440101-B1 POLYURETHANE, METHOD FOR PRODUCTION AND USE THEREOF BASF COATINGS AG (DE) 2007-01-31 EP claimed
EP-1311628-B1 PSEUDOPLASTIC POWDERED LACQUER SLURRY FREE OF ORGANIC SOLVENTS AND EXTERNAL EMULSIFIERS, METHOD FOR PRODUCTION AND USE THEREOF BASF COATINGS AG (DE) 2006-10-25 EP claimed
EP-1311580-B1 SINGLE COMPONENT SYSTEM SETTING BY THERMAL MEANS OR BY ACTINIC IRRADIATION AND USE THEREOF BASF COATINGS AG (DE) 2006-06-28 EP claimed
US-6930155-B2 Powder coatings based on thermoset-modified polymers and polyesters DEGUSSA AG (DE) 2005-08-16 US claimed
EP-1127905-B1 Transparent or pigmented powder coatings with crosslinkers from hydroxyalkylamides and blocked non-aromatic polyisocyanates DEGUSSA (DE) 2005-03-09 EP claimed
JP-2005504157-A 2005-02-10 JP claimed
EP-1440101-A1 POLYURETHANE, METHOD FOR PRODUCTION AND USE THEREOF BASF Coatings AG (DE) 2004-07-28 EP claimed
US-20040014881-A1 Single component system setting thermal means or by actinic irradiation and use thereof BASF COATINGS AKTIENGESELLSCHAFT (DE) 2004-01-22 US claimed
EP-1362873-A1 Powder coatings based on polyesters and thermoset modified polyesters Degussa AG (DE) 2003-11-19 EP claimed
US-6500548-B2 POWDER COATING DEGUSSA AG (DE) 2002-12-31 US claimed
WO-2002016462-A1 SINGLE COMPONENT SYSTEM SETTING BY THERMAL MEANS OR BY ACTINIC IRRADIATION AND USE THEREOF BASF COATINGS AG (DE) 2002-02-28 WO claimed
WO-2002014440-A2 PSEUDOPLASTIC POWDERED LACQUER SLURRY FREE OF ORGANIC SOLVENTS AND EXTERNAL EMULSIFIERS, METHOD FOR PRODUCTION AND USE THEREOF BASF COATINGS AG (DE) 2002-02-21 WO claimed
US-20010021748-A1 Transparent or pigmented powder coating materials with crosslinkers comprising hydroxyalkylamides and blocked nonaromatic polyisocyanates DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2001-09-13 US claimed
EP-1127905-A1 Transparent or pigmented powder coatings with crosslinkers from hydroxyalkylamides and blocked non-aromatic polyisocyanates Degussa AG (DE) 2001-08-29 EP claimed
US-6063497-A BASED ON EPOXY RESINS HAVING 1,2-EPOXIDE GROUPS AND HYDROXYL GROUP(S) IN THE RESIN, AND CURING AGENTS INCLUDING POLYISOCYANATES BLOCKED WITH INERT AGENTS AND CYCLIC AMIDINE(S) OF GIVEN FORMULA; HEAT STABILITY, SOLVENT RESISTANT HUELS AKTIENGESELLSCHAFT (DE) 2000-05-16 US claimed
EP-0818486-A1 Powder compounds, a process for their preparation as well as their use HÜLS AKTIENGESELLSCHAFT (DE) 1998-01-14 EP claimed
US-4734310-A Sheet of artificial leather made of polyvinyl chloride, the back of which is coated with a dry adhesive capable of being activated by heat, and use of this sheet for thermocovering of rigid articles SOLVAY & CIE (BE) 1988-03-29 US claimed
US-4668360-A Process for electrocoating water reducible quaternary ammonium salt containing polymers THE SHERWIN-WILLIAMS COMPANY (US) 1987-05-26 US claimed
US-4561952-A Water reducible quaternary ammonium salt containing polymers THE SHERWIN-WILLIAMS COMPANY (US) 1985-12-31 US claimed