Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 13/20 | 0.49 |
| ▸ | CTSS | P25774 | 9/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271432 | 1.00 | CTSK (0.54) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL6285900 | 1.00 | CTSK (0.54) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL6271426 | 1.00 | CTSK (0.54) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL6271433 | 1.00 | CTSK (0.54) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL4320431 | 0.90 | CTSK (0.56) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL4320412 | 0.90 | CTSK (0.56) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL4314731 | 0.87 | TAS1R3 (0.61) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL4318551 | 0.87 | TAS1R3 (0.61) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL5092508 | 0.87 | CTSK (0.60) | CTSKTAS1R3TAS1R1CTSLCTSS | |
| SCHEMBL5092490 | 0.87 | CTSK (0.60) | CTSKTAS1R3TAS1R1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005013909-A2 | NOVEL CATHEPSIN K INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-17 | — | — | WO | disclosed |