SCHEMBL6285984

SCHEMBL6285984

C[Si](C)(C)C#CCCOC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7645955 0.76
SCHEMBL7645554 0.74 PTPN7 (0.32)
SCHEMBL6272882 0.71 EPHX2 (0.38)
SCHEMBL7315206 0.68 PTPN7 (0.50)
SCHEMBL23532681 0.68
SCHEMBL5260493 0.67 CHRM1 (0.48)
SCHEMBL791108 0.67 USP2 (0.44)
SCHEMBL7648337 0.66
SCHEMBL1961552 0.66
Bicarbonate SCHEMBL6285987 0.66 FFAR3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6867161-B1 Titanium catalyst and organotitanium reacting reagent, production thereof, and reaction thereby NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-03-15 US disclosed
EP-0820809-A1 TITANIUM CATALYST, ORGANOTITANIUM REACTION REAGENT, PROCESSES FOR PRODUCING THESE, AND METHOD OF REACTION USING THESE NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-01-28 EP disclosed