Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL167201 | 0.76 | FFAR3 (0.44) | FFAR3GRIK1GRIK2 | |
| Bicarbonate SCHEMBL15967910 | 0.76 | FFAR3 (0.44) | FFAR3GRIK1GRIK2 | |
| SCHEMBL12621542 | 0.70 | — | — | |
| SCHEMBL6272882 | 0.70 | EPHX2 (0.38) | FFAR3 | |
| Bicarbonate SCHEMBL5538707 | 0.69 | — | — | |
| SCHEMBL73409 | 0.69 | — | — | |
| SCHEMBL31627275 | 0.67 | — | — | |
| SCHEMBL31627244 | 0.67 | — | — | |
| SCHEMBL7315206 | 0.67 | PTPN7 (0.50) | — | |
| Hydrochloric Acid SCHEMBL1569440 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867161-B1 | Titanium catalyst and organotitanium reacting reagent, production thereof, and reaction thereby | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| EP-0820809-A1 | TITANIUM CATALYST, ORGANOTITANIUM REACTION REAGENT, PROCESSES FOR PRODUCING THESE, AND METHOD OF REACTION USING THESE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1998-01-28 | — | — | EP | disclosed |