Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625843 | 0.73 | ESR1 (0.58) | ESR1ESR2 | |
| SCHEMBL6797161 | 0.73 | ESR1 (0.58) | ESR1ESR2 | |
| SCHEMBL6796544 | 0.73 | ESR1 (0.57) | ESR1ESR2 | |
| SCHEMBL699174 | 0.71 | ESR1 (0.76) | ESR1ESR2 | |
| SCHEMBL1359959 | 0.71 | ESR1 (0.76) | ESR1ESR2 | |
| SCHEMBL2475993 | 0.70 | ESR1 (0.75) | ESR1ESR2 | |
| SCHEMBL6801025 | 0.70 | HRH3 (0.57) | ESR1ESR2 | |
| SCHEMBL7458270 | 0.69 | ESR1 (0.68) | ESR1ESR2 | |
| SCHEMBL6799341 | 0.69 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL5070352 | 0.68 | ESR1 (0.59) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838584-B2 | Estrogen receptor modulators | MERCK & CO., INC. (US) | 2005-01-04 | — | — | US | disclosed |
| US-20040162304-A1 | Estrogen receptor modulators | MERCK & CO., INC. | 2004-08-19 | — | — | US | disclosed |
| EP-1387821-A2 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002091993-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162304-A1 | Estrogen receptor modulators | ESRRA, GPER1, ESRRB | ESR1 5/4885ESR2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.