Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.62 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280728 | 0.81 | PDE7A (0.63) | PDE7APDE7BNPSR1ALOX12MEN1 | |
| SCHEMBL10550539 | 0.80 | HTT (0.76) | PDE7APDE7BNPSR1ALOX12MEN1 | |
| SCHEMBL21436060 | 0.78 | ALOX12 (0.70) | PDE7APDE7BNPSR1ALOX12MEN1 | |
| SCHEMBL6282188 | 0.78 | PDE7A (0.63) | PDE7APDE7BNPSR1ALOX12MEN1 | |
| SCHEMBL18239972 | 0.78 | HTT (0.67) | PDE7APDE7BNPSR1ALOX12MEN1 | |
| SCHEMBL6283505 | 0.78 | PDE7A (0.77) | PDE7APDE7BNPSR1ALOX12MEN1 | |
| SCHEMBL30103233 | 0.77 | PDE7A (1.00) | PDE7APDE7BNPSR1MEN1KMT2A | |
| SCHEMBL844588 | 0.77 | PDE7A (1.00) | PDE7APDE7BNPSR1MEN1KMT2A | |
| SCHEMBL6284203 | 0.77 | PDE7A (0.61) | PDE7APDE7BNPSR1ALOX12MEN1 | |
| SCHEMBL6981997 | 0.75 | KDM4E (0.74) | PDE7APDE7BNPSR1ALOX12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020178-A1 | NOVEL HETEROCYCLES AS CHOLECYSTOKININ (CCK) LIGANDS | WARNER-LAMBERT COMPANY (US) | 1996-07-04 | — | — | WO | claimed |
| US-6897213-B1 | Heterocycles as cholecystokinin (CCK) ligands | WARNER-LAMBERT COMPANY (US) | 2005-05-24 | — | — | US | disclosed |
| WO-1996020178-A1 | NOVEL HETEROCYCLES AS CHOLECYSTOKININ (CCK) LIGANDS | WARNER-LAMBERT COMPANY (US) | 1996-07-04 | — | — | WO | disclosed |