SCHEMBL6286732

SCHEMBL6286732

CNCC(CNC)(CNC)CNC(=O)NC

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.34
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6289690 0.89 HSD17B10 (0.32) HSD17B10KEAP1NFE2L2
SCHEMBL6285467 0.82 ALDH1A1 (0.37) KMT2A
SCHEMBL6290232 0.81 HSD17B10 (0.34) HSD17B10KEAP1NFE2L2KMT2A
SCHEMBL6284472 0.80 HSD17B10 (0.32) HSD17B10KEAP1NFE2L2
SCHEMBL6286736 0.79 HSD17B10 (0.33) HSD17B10KEAP1NFE2L2
SCHEMBL6285495 0.79 HSD17B10 (0.39) HSD17B10KEAP1NFE2L2
SCHEMBL6289599 0.76 TDP1 (0.33)
SCHEMBL6290265 0.76 HSD17B10 (0.32) HSD17B10KEAP1NFE2L2
SCHEMBL6290189 0.76 EPHX1 (0.57)
SCHEMBL9278494 0.75 HSD17B10 (0.36) HSD17B10KEAP1NFE2L2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed