SCHEMBL6290265

SCHEMBL6290265

CCC(CO)(CO)CNC(=O)NC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.32
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290232 0.89 HSD17B10 (0.34) HSD17B10KEAP1NFE2L2
SCHEMBL6289690 0.83 HSD17B10 (0.32) HSD17B10KEAP1NFE2L2
SCHEMBL6284467 0.83 ALDH1A1 (0.32)
SCHEMBL6289695 0.80 HSD17B10 (0.30) HSD17B10
SCHEMBL6283759 0.77 EPHX1 (0.55)
SCHEMBL6289548 0.77 TDP1 (0.31)
SCHEMBL6286732 0.76 HSD17B10 (0.34) HSD17B10KEAP1NFE2L2
SCHEMBL6284472 0.75 HSD17B10 (0.32) HSD17B10KEAP1NFE2L2
SCHEMBL6286748 0.74 EPHX1 (0.39)
SCHEMBL6289587 0.74 CHRM2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed