Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615098 | 1.00 | MGLL (0.57) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL1615619 | 0.98 | MGLL (0.58) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL7636433 | 0.98 | MGLL (0.58) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL28225373 | 0.98 | MGLL (0.58) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL11288705 | 0.98 | MGLL (0.58) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL5067073 | 0.96 | LMNA (0.57) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL138018 | 0.92 | LMNA (0.59) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL471890 | 0.90 | MGLL (0.60) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL936727 | 0.90 | MGLL (0.60) | MGLLALDH1A1LMNAPOLB | |
| SCHEMBL1715123 | 0.90 | MGLL (0.60) | MGLLALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972068-B1 | Method for the surface treatment of a fluorine resin, method for making a laminate, and a laminate | BRIDGESTONE CORPORATION (JP) | 2005-12-06 | — | — | US | disclosed |
| EP-1099532-B1 | Method of surface treating and laminating a fluorine resin | BRIDGESTONE CORP (JP) | 2004-06-16 | — | — | EP | disclosed |
| EP-1099532-A2 | Method for the surface treatment of a fluorine resin, Method for making a laminate, and a laminate | Bridgestone Corporation (JP) | 2001-05-16 | — | — | EP | disclosed |