SCHEMBL6286903

SCHEMBL6286903

CC(C)(C)c1c(OCCO)ccc(-n2nc3ccc(C(F)(F)F)cc3n2)c1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.36
▸ KDM4E B2RXH2 3/20 0.32
▸ HTT P42858 2/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ PTGDR2 Q9Y5Y4 3/20 0.32
▸ CYP19A1 P11511 1/20 0.31
▸ CYP11B1 P15538 1/20 0.31
▸ CYP11B2 P19099 1/20 0.31
▸ IDO1 P14902 1/20 0.31
▸ TDO2 P48775 1/20 0.31
▸ NR1I2 O75469 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ DYRK3 O43781 2/20 0.31
▸ CCNA2 P20248 2/20 0.31
▸ CDK2 P24941 2/20 0.31
▸ DYRK1A Q13627 2/20 0.31
▸ DYRK2 Q92630 2/20 0.31
▸ DYRK1B Q9Y463 2/20 0.31
▸ CCNT1 O60563 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6286959 0.85 KDM4E (0.34) KDM4EHTTKMT2A
SCHEMBL13700598 0.76 ADRB2 (0.34) KDM4ECYP19A1CYP11B1CYP11B2POLB
SCHEMBL15393589 0.74 SRC (0.33) KDM4EPKM
SCHEMBL9869771 0.73 KDM4E (0.41) CNR2KDM4EHTTKMT2ANR1I2
SCHEMBL13700540 0.72 MIF (0.37) KDM4EPOLBSCN9AMC4R
SCHEMBL13700597 0.71 POLB (0.36) KDM4EKMT2APOLBSCN9AMC4R
SCHEMBL2637886 0.71 ALDH1A1 (0.35) KDM4EHTTKMT2APOLBPKM
SCHEMBL27481690 0.70 NPC1 (0.46) KDM4EKMT2APKMCCNA2CDK2
SCHEMBL2639325 0.69 ALDH1A1 (0.34) KDM4EHTTKMT2APOLBPKM
SCHEMBL29358804 0.69 KDM4E (0.38) KDM4ENR1I2POLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050171253-A1 Containers or films comprising hydroxyphenlbenzotriazole uv absorbers for protecting contents against the effects of uv radiation CIBA SPECIALTY CHEMICALS CORP. 2005-08-04 — — US claimed
JP-2005517787-A — — 2005-06-16 — — JP claimed
EP-1476503-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENYLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION Ciba SC Holding AG (CH) 2004-11-17 — — EP claimed
WO-2003070819-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-08-28 — — WO claimed
US-8912287-B2 Method for producing polymer using monomer having piperidine skeleton, and molded body MITSUBISHI RAYON CO., LTD. (JP) 2014-12-16 — — US disclosed
EP-2508542-A1 METHOD OF PRODUCING A POLYMER USING MONOMERS HAVING A PIPERIDINE SKELETON, AND MOLDED BODY Mitsubishi Rayon Co., Ltd. (JP) 2012-10-10 — — EP disclosed
US-20120245318-A1 METHOD FOR PRODUCING POLYMER USING MONOMER HAVING PIPERIDINE SKELETON, AND MOLDED BODY MITSUBISHI RAYON CO., LTD. (JP) 2012-09-27 — — US disclosed
US-20050171253-A1 Containers or films comprising hydroxyphenlbenzotriazole uv absorbers for protecting contents against the effects of uv radiation CIBA SPECIALTY CHEMICALS CORP. 2005-08-04 — — US disclosed
EP-1476503-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENYLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION Ciba SC Holding AG (CH) 2004-11-17 — — EP disclosed
WO-2003070819-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-08-28 — — WO disclosed
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