Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557210 | 0.99 | ALDH1A1 (0.61) | ALDH1A1MAPTCYP2C19HTTNPSR1 | |
| SCHEMBL4994038 | 0.96 | ALDH1A1 (0.67) | ALDH1A1MAPTCYP2C19HTTNPSR1 | |
| SCHEMBL4999081 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTCYP2C19HTTNPSR1 | |
| SCHEMBL4987745 | 0.82 | RECQL (0.67) | ALDH1A1MAPTSMN1; SMN2KMT2ATDP1 | |
| SCHEMBL16314622 | 0.81 | USP2 (0.65) | MAPTHTTFKBP1ASMN1; SMN2KMT2A | |
| SCHEMBL9557181 | 0.81 | CYP1A2 (0.65) | ALDH1A1MAPTCYP2C19HTTFKBP1A | |
| SCHEMBL1953978 | 0.81 | FKBP1A (0.80) | MAPTNPSR1FKBP1ASMN1; SMN2TDP1 | |
| SCHEMBL6287115 | 0.80 | KMT2A (0.54) | ALDH1A1MAPTCYP2C19HTTNPSR1 | |
| SCHEMBL9556702 | 0.80 | FKBP1A (0.78) | MAPTNPSR1FKBP1ASMN1; SMN2TDP1 | |
| SCHEMBL4404789 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPTCYP2C19HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846925-B2 | Colchinol derivatives as angiogenesis inhibitors | ANGIOGENE PHARMACEUTICALS LIMITED (GB) | 2005-01-25 | — | — | US | disclosed |