SCHEMBL6287617

SCHEMBL6287617

CCNC(=O)NCCCOCCCNC

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TSHR P16473 1/20 0.44
EPHX1 P07099 5/20 0.44
EPHX2 P34913 7/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290340 0.89 EPHX1 (0.57) MAPTHSD17B10EPHX1EPHX2
SCHEMBL6285139 0.86 EPHX1 (0.58) EPHX1EPHX2
SCHEMBL6284640 0.86 EPHX1 (0.52) EPHX1EPHX2
SCHEMBL6287189 0.85 MAPT (0.44) MAPTHSD17B10TSHREPHX1EPHX2
SCHEMBL6287295 0.85 MAPT (0.44) MAPTHSD17B10TSHREPHX1EPHX2
SCHEMBL6283536 0.85 MEN1 (0.41) MAPTHSD17B10EPHX1EPHX2
SCHEMBL6286750 0.85 KEAP1 (0.43) MAPTHSD17B10TSHREPHX1EPHX2
SCHEMBL6287207 0.84 EPHX1 (0.61) EPHX1EPHX2
SCHEMBL22260405 0.84 KDM4E (0.47) MAPTHSD17B10TSHREPHX1EPHX2
SCHEMBL6289746 0.83 MEN1 (0.44) EPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed