Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290323 | 0.86 | KEAP1 (0.42) | KEAP1NFE2L2MAPTHSD17B10TSHR | |
| SCHEMBL6285158 | 0.85 | KEAP1 (0.55) | KEAP1NFE2L2EPHX1 | |
| SCHEMBL6287670 | 0.85 | KEAP1 (0.50) | KEAP1NFE2L2HSD17B10EPHX1 | |
| SCHEMBL6290340 | 0.85 | EPHX1 (0.57) | MAPTHSD17B10EPHX2EPHX1 | |
| SCHEMBL6287617 | 0.85 | MAPT (0.44) | MAPTHSD17B10TSHREPHX2EPHX1 | |
| SCHEMBL6290526 | 0.83 | KMT2A (0.44) | KEAP1NFE2L2MAPTHSD17B10EPHX2 | |
| SCHEMBL6280459 | 0.83 | MAPT (0.43) | KEAP1NFE2L2MAPTHSD17B10TSHR | |
| SCHEMBL6289749 | 0.83 | EPHX1 (0.54) | KEAP1NFE2L2EPHX1 | |
| SCHEMBL6284129 | 0.82 | MAPT (0.49) | MAPTHSD17B10EPHX2EPHX1 | |
| SCHEMBL21997079 | 0.82 | ALDH1A1 (0.41) | MAPTHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |