SCHEMBL628776

SCHEMBL628776

N#CC1CCC(=O)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11357423 0.89 CYP11B2 (0.36)
SCHEMBL17260763 0.89 TRIM24 (0.43)
SCHEMBL17260812 0.87 TRIM24 (0.46)
SCHEMBL17260750 0.87 TRIM24 (0.46)
SCHEMBL19951605 0.84
SCHEMBL329065 0.84 TRIM24 (0.43)
SCHEMBL14842917 0.74
SCHEMBL28881361 0.74
SCHEMBL12183121 0.72
SCHEMBL6618 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113789527-B Electrochemical synthesis method of aromatic amine 四川大学 2023-02-28 CN claimed
CN-113789527-A Electrochemical synthesis method of aromatic amine 四川大学 2021-12-14 CN claimed
US-20260098032-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION PMV PHARMACEUTICALS INC (US) 2026-04-09 US disclosed
US-12595253-B2 Benzamides of pyrazolylamino-pyrimidinyl derivatives, and compositions and methods thereof LYNK PHARMACEUTICALS CO. LTD. (CN) 2026-04-07 US disclosed
US-12583858-B2 TDO2 inhibitors GENENTECH, INC. (US) 2026-03-24 US disclosed
EP-4663640-A1 XANTHINE COMPOUND AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2025-12-17 EP disclosed
EP-4644387-A2 METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION PMV Pharmaceuticals, Inc. (US) 2025-11-05 EP disclosed
US-20250320224-A1 NOVEL PAR-2 INHIBITORS DOMAIN THERAPEUTICS (FR) 2025-10-16 US disclosed
US-12428406-B2 Methods and compounds for restoring mutant p53 function PMV PHARMACEUTICALS, INC. (US) 2025-09-30 US disclosed
US-12421213-B2 Benzamides of pyrazolylamino- pyrimidinyl derivatives, and compositions and methods thereof LYNK PHARMACEUTICALS CO. LTD. (CN) 2025-09-23 US disclosed
US-12358887-B2 IKAROS Zinc Finger Family degraders and uses thereof GILEAD SCIENCES, INC. (US) 2025-07-15 US disclosed
WO-1998045268-A1 NICOTINAMIDE DERIVATIVES PFIZER PRODUCTS INC. (US) 1998-10-15 WO disclosed
US-4783280-A Liquid crystal mixture HOFFMANN-LA ROCHE INC. (US) 1988-11-08 US disclosed
US-4708441-A LIQUID CRYSTALS HOFFMAN-LA ROCHE INC. (US) 1987-11-24 US disclosed
US-4550981-A Liquid crystalline esters and mixtures HOFFMANN-LA ROCHE INC. (US) 1985-11-05 US disclosed
EP-0056113-B1 CYCLOHEXYLCARBONITRILE DERIVATIVES, DIELECTRICS AND ELECTRO-OPTIC DISPLAY DEVICE CONTAINING THEM MERCK PATENT GmbH (DE) 1985-05-29 EP disclosed
US-4460770-A Liquid crystal mixture HOFFMANN-LA ROCHE INC. (US) 1984-07-17 US disclosed
US-4419263-A Liquid crystalline cyclohexylcarbonitrile derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-12-06 US disclosed
EP-0056113-A1 Cyclohexylcarbonitrile derivatives, dielectrics and electro-optic display device containing them MERCK PATENT GmbH (DE) 1982-07-21 EP disclosed
EP-0034415-A1 1-(Cyclohexyl or cyclohexenyl)-4-aryl-4-piperidinecarboxylic acid derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1981-08-26 EP disclosed