Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 12/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247594 | 0.93 | LMNA (0.44) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL6280238 | 0.83 | LMNA (0.43) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL5244778 | 0.83 | EPHX1 (0.45) | TSHRNFKB1ACHEPOLBSMN1; SMN2 | |
| SCHEMBL5245027 | 0.83 | ACHE (0.54) | ACHEALOX15GAA | |
| SCHEMBL6287636 | 0.82 | LMNA (0.56) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL6290258 | 0.82 | LMNA (0.47) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL5246483 | 0.81 | ACHE (0.45) | TSHRACHEALOX15 | |
| SCHEMBL5244908 | 0.78 | LMNA (0.44) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL6287064 | 0.77 | EPHX1 (0.36) | TSHRACHEALOX15POLBSMN1; SMN2 | |
| SCHEMBL20104322 | 0.76 | LMNA (0.54) | LMNAHSD17B10TSHRCYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |