Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298487 | 0.86 | AKR1B1 (0.39) | ACHEMAPTCYP3A4CA9ALDH1A1 | |
| SCHEMBL12653142 | 0.82 | ACHE (0.48) | ACHEMAPTCYP3A4CA9ALDH1A1 | |
| SCHEMBL11560455 | 0.82 | ACHE (0.48) | ACHEMAPTCYP3A4CA9ALDH1A1 | |
| SCHEMBL29749746 | 0.80 | CYP3A4 (0.50) | ACHECYP3A4ALDH1A1HPGDAKR1B1 | |
| SCHEMBL481060 | 0.80 | CYP3A4 (0.50) | ACHECYP3A4ALDH1A1HPGDAKR1B1 | |
| SCHEMBL914797 | 0.80 | CYP3A4 (0.50) | MAPTCYP3A4ALDH1A1HPGDAKR1B1 | |
| SCHEMBL29749799 | 0.80 | CYP3A4 (0.50) | MAPTCYP3A4ALDH1A1HPGDAKR1B1 | |
| SCHEMBL9348568 | 0.79 | ACHE (0.50) | ACHEMAPTCYP3A4CA9ALDH1A1 | |
| SCHEMBL13747922 | 0.79 | ACHE (0.40) | ACHEMAPTCYP3A4CA9ALDH1A1 | |
| SCHEMBL11565304 | 0.77 | CYP3A4 (0.52) | ACHEMAPTCYP3A4CA9TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005350479-A | ZINC(II) PORPHYRIN DERIVATIVE | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL & TECHNOLOGY | 2005-12-22 | — | — | JP | disclosed |
| US-5481815-A | APPARATUS FOR TREATING SEDIMENT IN A WATER BODY | HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF THE ENVIRONMENT (CA) | 1996-01-09 | — | — | US | disclosed |