SCHEMBL481060

SCHEMBL481060

COc1c(Cl)cc(Cl)c(Cl)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.50
HPGD P15428 4/20 0.40
HSD17B10 Q99714 4/20 0.40
TSHR P16473 3/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
TPMT P51580 1/20 0.39
NPC1 O15118 1/20 0.38
CASP1 P29466 1/20 0.38
CHUK O15111 1/20 0.38
DRD2 P14416 1/20 0.37
DRD1 P21728 1/20 0.37
DRD5 P21918 1/20 0.37
DRD3 P35462 1/20 0.37
HSP90AA1 P07900 1/20 0.35
AKR1B1 P15121 2/20 0.34
TDP1 Q9NUW8 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29749746 1.00 CYP3A4 (0.50) CYP3A4HPGDHSD17B10TSHRMAPK1
SCHEMBL21614387 0.89 ALDH1A1 (0.42) CYP3A4HPGDHSD17B10TSHRALDH1A1
SCHEMBL8640622 0.83 CYP3A4 (0.47) CYP3A4HPGDHSD17B10TSHRMAPK1
SCHEMBL23972200 0.80 ALDH1A1 (0.37) CYP3A4HPGDHSD17B10MAPK1ALDH1A1
SCHEMBL28574488 0.80 DRD2 (0.38) CYP3A4HPGDHSD17B10MAPK1ALDH1A1
SCHEMBL6288225 0.80 ACHE (0.46) CYP3A4HPGDALDH1A1GAANPC1
SCHEMBL10946322 0.78 GAA (0.48) CYP3A4HPGDALDH1A1KDM4EGAA
SCHEMBL9331965 0.78 HPGD (0.56) CYP3A4HPGDHSD17B10TSHRMAPK1
SCHEMBL10947660 0.78 GAA (0.48) CYP3A4HSD17B10ALDH1A1KDM4EGAA
SCHEMBL23214922 0.78 CA2 (0.46) CYP3A4HPGDHSD17B10TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3698396-B1 SAMPLER FOR SEQUENTIALLY COLLECTING ANALYTES FROM INDIVIDUAL SAMPLES, E.G. CORK STOPPERS TOFWERK AG (CH) 2026-03-18 EP claimed
EP-4513196-A2 ION MOLECULE REACTOR AND SETUP FOR ANALYZING COMPLEX MIXTURES Tofwerk AG (CH) 2025-02-26 EP claimed
US-20240194470-A1 ION MOLECULE REACTOR AND SETUP FOR ANALYZING COMPLEX MIXTURES TOFWERK AG (CH) 2024-06-13 US claimed
CN-112098558-B Method for simultaneously determining various cork pollutants in wine 秦皇岛海关技术中心 2022-07-01 CN claimed
CN-112098558-A Method for simultaneously determining various cork pollutants in wine 秦皇岛海关技术中心 2020-12-18 CN claimed
EP-3698396-A1 ION MOLECULE REACTOR AND SETUP FOR ANALYZING COMPLEX MIXTURES Tofwerk AG (CH) 2020-08-26 EP claimed
US-20200243317-A1 ION MOLECULE REACTOR AND SETUP FOR ANALYZING COMPLEX MIXTURES TOFWERK AG (CH) 2020-07-30 US claimed
CN-111386591-A Ionic molecular reactor and apparatus for analyzing complex mixtures 托夫沃克股份公司 2020-07-07 CN claimed
WO-2019077138-A1 ION MOLECULE REACTOR AND SETUP FOR ANALYZING COMPLEX MIXTURES TOFWERK AG (CH) 2019-04-25 WO claimed
WO-2019076490-A1 ION MOLECULE REACTOR AND SETUP FOR ANALYZING COMPLEX MIXTURES TOFWERK AG (CH) 2019-04-25 WO claimed
EP-2033751-B1 Method of treating cork or a cork-based material using an inert gas under a pressure strictly lower than 1 MPa. DIAM BOUCHAGE (FR) 2012-02-01 EP claimed
EP-2255182-A1 METHOD OF MONITORING THE CONTAMINATION OF BARRELS Laboratoire Excell (FR) 2010-12-01 EP claimed
WO-2010040949-A1 PROCESS FOR THE EXTRACTION OF UNDESIRABLE AROMATIC MOLECULES FROM CORK VIA A THERMO-HYDRO-MECHANICAL TREATMENT OF INSTANTANEOUS CONTROLLED PRESSURE DROP (DIC) OPTIONALLY IN SUCCESSIVE FORM (EDS) UNIVERSITE DE LA ROCHELLE (FR) 2010-04-15 WO claimed
WO-2009103640-A1 METHOD OF MONITORING THE CONTAMINATION OF BARRELS LABORATOIRE EXCELL (FR) 2009-08-27 WO claimed
US-20090130254-A1 Process for Removal of Toxic or Undersirable Polyhalogenated Compounds in Beverages, Especially in Wine VECT'OEUR (SARL) (FR) 2009-05-21 US claimed
EP-2033751-A1 Method of treating cork or a cork-based material using an inert gas under a pressure strictly lower than 1 MPa. OENEO BOUCHAGE (FR) 2009-03-11 EP claimed
EP-1778396-A1 METHOD FOR ELIMINATING TOXIC OR UNDESIRABLE POLYHALOGENATED COMPOUNDS FROM DRINKS, ESPECIALLY WINE Vect'Oeur (Sarl) (FR) 2007-05-02 EP claimed
WO-2006024767-A1 METHOD FOR ELIMINATING TOXIC OR UNDESIRABLE POLYHALOGENATED COMPOUNDS FROM DRINKS, ESPECIALLY WINE VECT'OEUR (SARL) (FR) 2006-03-09 WO claimed
WO-2004079107-A2 METHOD FOR REDUCING ODOUR LEVEL OR POLLUTANT EMISSIONS IN INSIDE AREAS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2004-09-16 WO claimed
US-4346244-A Preparation of chloroalkoxybenzenes RHONE-POULENC INDUSTRIES (FR) 1982-08-24 US claimed