Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.53 |
| ▸ | PPARA | Q07869 | 16/20 | 0.53 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6288254 | 0.80 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL14395176 | 0.79 | PPARA (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5210093 | 0.79 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL6699626 | 0.77 | PPARA (0.77) | PPARGPPARAPPARD | |
| SCHEMBL6985710 | 0.73 | PPARA (0.74) | PPARGPPARAPPARD | |
| SCHEMBL6702308 | 0.73 | PPARA (0.62) | PPARGPPARAPPARD | |
| SCHEMBL5210369 | 0.73 | PPARA (0.79) | PPARGPPARAPPARD | |
| SCHEMBL5210370 | 0.73 | PPARA (0.87) | PPARGPPARAPPARD | |
| SCHEMBL5208786 | 0.72 | PPARA (0.81) | PPARGPPARAPPARD | |
| SCHEMBL5208722 | 0.72 | PPARA (0.72) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | claimed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | claimed |
| EP-1313717-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016332-A1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |